Inside The absence of the enzyme, as in Crigler-Najjar syndrome style I, the levels of unconjugated bilirubin will rise, bringing about jaundice. Unconjugated bilirubin is h2o-insoluble, and significant concentrations can deposit during the Mind leading to a situation referred to as kernicterus. Severe hyperbilirubinemia normally develops in the primary couple https://www.youtube.com/shorts/IuPMi7CvqAo