Introduction: Previous studies have shown that the cannabinoid system is involved in anxiety. In addition. transient receptor potential vanilloid type-1 (TRPV1) channels are new targets for the development of anxiolytics. The present study investigated the possible interaction between the cannabinoid and vanilloid systems on anxiety-like behavior in rats. https://www.wholisticpet.shop/product-category/feline-toys-wands/